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Endocrine Abstracts

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ea0034p345 | Steroids | SFEBES2014

Role of estrogen hormone in lipopolysaccharide: induced Alzheimer's disease in female rats; possible underlying mechanisms and modulation by progesterone hormone

Abdelwahed O M , Gamal M , Abdelwahab Z , Zickri M , El Eraky W , Saleh D O

The incidence of Alzheimer’s disease (AD) is higher in women than men. Our study aimed to investigate the behavioral, biochemical, and histological changes in lipopolysaccharide (LPS)-induced AD, to study effect of estrogen in AD clarifying the possible involved underlying mechanisms and its modulation by progestsserone. Groups: Female albino rats were divided into control, AD, AD+ovariectomy (OVX), AD+OVX+estrogen replacement and AD+OVX+estrogen+pr...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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